{"id":8060,"date":"2020-11-30T14:04:46","date_gmt":"2020-11-30T14:04:46","guid":{"rendered":"https:\/\/www.innovationnewsnetwork.com\/?p=8060"},"modified":"2020-11-30T14:11:45","modified_gmt":"2020-11-30T14:11:45","slug":"study-of-worms-in-space-show-that-gravity-impacts-genes","status":"publish","type":"post","link":"https:\/\/www.innovationnewsnetwork.com\/study-of-worms-in-space-show-that-gravity-impacts-genes\/8060\/","title":{"rendered":"Study of worms in space shows that gravity impacts genes"},"content":{"rendered":"<h2>A study of worms in space conducted by the University of Exeter and the NASA GeneLab reveals that a low gravity environment affects cells at a genetic level.<\/h2>\n<p>Genetic analysis of Caenorhabditis elegans worms on the International Space Station showed small changes in about 1,000 genes.<\/p>\n<p>The <a href=\"https:\/\/www.cell.com\/iscience\/fulltext\/S2589-0042(20)30931-7\">study<\/a> indicates that not all genes were affected in the same way; more prominent effects were found in genes such as neurons (nervous system cells).<\/p>\n<p>Researchers believe that this discovery will aid our understanding of why living organisms, including humans, suffer physical decline in space.<\/p>\n<p>Dr Timothy Etheridge, of the University of Exeter said: \u201cWe looked at levels of every gene in the worms&#8217; genome and identified a clear pattern of genetic change.<\/p>\n<p>&#8220;These changes might help explain why the body reacts badly to space flight.<\/p>\n<p>&#8220;It also gives us some therapy targets in terms of reducing these health effects, which are currently a major barrier to deep-space exploration.&#8221;<\/p>\n<p>The worms were subjected to a low-gravity environment on the <a href=\"https:\/\/www.innovationnewsnetwork.com\/new-project-to-apply-sustainable-space-technologies-on-earth\/7416\/\">International Space Station<\/a> and to a high-gravity environment in centrifuges (laboratory devices used for the separation of fluids, gas or liquid, based on density).<\/p>\n<p>The high-gravity tests gave the researchers more data on gravity&#8217;s genetic impacts and allowed them to look for possible treatments using high gravity in space.<\/p>\n<p>Lead author, Craig Willis, of the University of Exeter said: &#8220;A crucial step towards overcoming any physiological condition is first understanding its underlying molecular mechanism.<\/p>\n<p>&#8220;We have identified genes with roles in neuronal function and cellular metabolism that are affected by gravitational changes.<\/p>\n<p>&#8220;These worms display molecular signatures and physiological features that closely mirror those observed in humans, so our findings should provide foundations for a better understanding of spaceflight-induced health decline in mammals and, eventually, humans.&#8221;<\/p>\n<p>Dr Etheridge added: &#8220;This study highlights the ongoing role of scientists from Europe and the UK in space flight life sciences research.&#8221;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A study of worms in space conducted by the University of Exeter and the NASA GeneLab reveals that a low gravity environment affects cells at a genetic level.<\/p>\n","protected":false},"author":13,"featured_media":8062,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[766,24429,771],"tags":[3475],"acf":[],"yoast_head":"\n<title>Study of worms in space shows that gravity impacts genes | Innovation News Network<\/title>\n<meta name=\"description\" content=\"A study of worms in space conducted by the University of Exeter reveals that a low gravity environment affects cells at a genetic level.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, 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